NRL Mouse anti-Human, Clone: OTI5H2, liquid, TrueMAB™

Catalog No.	Quantity
50-168-3553	100 μL

Catalog No. 50-168-3553 Supplier OriGene Supplier No. TA810651

Description

Mouse Monoclonal Antibody

Nrl (neural retina leucine zipper) is a member of the Maf family of transcription factors, which characteristically contain a highly conserved basic leucine zipper (bZIP)-DNA binding motif. Both Nrl and c-Maf preferentially bind to T-MARE sites and are implicated in a wide variety of developmental and physiologic roles. The Maf-Nrl subfamily regulates the expression of cell type-specific genes in tissues of the hematopoietic system, cerebellum and developing hindbrain. Maf and Nrl proteins bind an extended AP-1-like sequence and can form heterodimers with Fos and Jun transcription factors. In retinal cells and photoreceptor cells, Nrl promotes the expression of rhodopsin through binding to the Nrl response element present in the rhodopsin promoter. Nrl is expressed throughout the developing central and peripheral nervous system during neuronal differentiation, and its expression is restricted to neocortex, brainstem and retinal neurons during adulthood.

Specifications

• Antigen: NRL
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI5H2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: NRL
• Gene Accession No.: P54845
• Gene Alias: D14S46E, NRL-MAF, RP27
• Gene Symbols: NRL
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human NRL produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4901
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1