Tocris NS 9283
Positive allosteric modulator of alpha4beta2
Manufacturer: Tocris 5112/50
DescriptionPositive allosteric modulator of α4β2 receptor; increases the potency of Ach-evoked currents ~60 fold without effecting the maximum efficacy (HEK293-hα4β2 cells). Reduces the rate of recovery from desensitization and slows the rate of deactivation. Displays a synergistic effect on the Emax when given with NS206 at 3α:2β receptors.
- Chemical Name: 3-[3-(3-Pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
- Formula: C14H8N4O
- CAS Number: 913830-15-6
- Solubility: Soluble to 50mM in DMSO and to 20mM in 1eq. HCl
- Purity: >99
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok