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Invitrogen™ Hairy Cell Leukemia Monoclonal Antibody (DBA.44)
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Catalog No. PIMA126274
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6 mL
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PIMA126274 6 mL
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Catalog No. PIMA126274 Supplier Invitrogen™ Supplier No. MA126274
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Description

Mouse Monoclonal Antibody

Recommended positive controls: Tonsil.

Hairy Cell Leukemia (HCL) is a rare form of mature B-cell cancer characterized by the presence of abnormal B-cells known as 'hairy cells.' These cells have a distinct genetic profile that plays a significant role in the diagnosis and management of the disease. HCL includes variants such as the hairy cell leukemia variant (HCL-V) and splenic diffuse red pulp lymphoma (SDRPL), which are often detected through specific immunophenotyping and genetic analyses. One critical aspect of these analyses involves the use of flow cytometry to detect lambda light chain restriction among B-cells displaying bright CD11c positivity. Advances in genetic profiling using techniques like clonal analysis with consensus primer polymerase chain reaction (PCR) for heavy chain genes have further refined diagnostic precision, distinguishing HCL from its variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Hairy Cell Leukemia
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone DBA.44
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Tissue culture supernatant with 0.09% sodium azide
Gene NSA2
Gene Accession No. O95478
Gene Alias 5730427N09Rik; CDK105; FLJ94393; Hairy cell leukemia protein 1; HCLG1; HCL-G1; HUSSY29; HUSSY-29; L-name related protein; L-name-related protein 42; LNR42; NSA2; NSA2 ribosome biogenesis homolog; NSA2 ribosome biogenesis homolog (S. cerevisiae); NSA2, ribosome biogenesis homolog; Nsa2p; ribosome biogenesis protein NSA2 homolog; TGF beta-inducible nuclear protein; TGF beta-inducible nuclear protein 1; TGF-beta inducible nuclear protein; TGF-beta-inducible nuclear protein 1; Tinp1; Yr29; YR-29
Gene Symbols NSA2
Host Species Mouse
Immunogen DEAU cell line established from a large cell lymphoma.
Purification Method Purified
Quantity 6 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10412
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgM
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