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Tocris Bioscience™ NSC 663284

Catalog No. 186710
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Catalog No. Quantity
18-671-0 10 mg
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Catalog No. 18-671-0 Supplier Tocris Bioscience™ Supplier No. 1867/10
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Description

Potent, selective Cdc25 phosphatase inhibitor

Potent, selective inhibitor of Cdc25 dual specificity phosphatases (Ki values are 29, 95 and 89 nM for human Cdc25A, Cdc25B2 and Cdc25C respectively); > 20- and > 450-fold selective over VHR and PTP1B phosphatases respectively. Arrests cells at both G1 and G2/M phase and blocks cdk2 and cdk1 activation. Blocks proliferation of a range of human tumor cell lines (IC50 = 0.2 - 35 μM).

Chemical Identifiers

CAS 383907-43-5
Molecular Formula C15H16ClN3O3

Specifications

Quantity 10 mg
Formula Weight 321.76
Purity >99%
Molecular Weight (g/mol) 321.76
Chemical Name or Material NSC 663284

Safety and Handling

Recommended Storage Store at +4°C
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