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Tocris Bioscience™ NSC 663284
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Catalog No. 186710
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent, selective Cdc25 phosphatase inhibitor

Potent, selective inhibitor of Cdc25 dual specificity phosphatases (Ki values are 29, 95 and 89 nM for human Cdc25A, Cdc25B2 and Cdc25C respectively); > 20- and > 450-fold selective over VHR and PTP1B phosphatases respectively. Arrests cells at both G1 and G2/M phase and blocks cdk2 and cdk1 activation. Blocks proliferation of a range of human tumor cell lines (IC50 = 0.2 - 35 μM).

Chemical Identifiers

CAS 383907-43-5
Molecular Formula C15H16ClN3O3

Specifications

Quantity 10 mg
Formula Weight 321.76
Purity >99%
Molecular Weight (g/mol) 321.76
Chemical Name or Material NSC 663284

Safety and Handling

Recommended Storage Store at +4°C
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