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NSC 95397, Tocris Bioscience™

Catalog No. p-4785259
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Catalog No. Quantity
15-471-0 10 mg
15-475-0 50 mg
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Catalog No. 15-471-0 Supplier R&D Systems Supplier No. 1547/10
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Description

Selective Cdc25 dual specificity phosphatase inhibitor

Potent and selective irreversible inhibitor of Cdc25 dual specificity phosphatases (Ki values are 32, 96 and 40 nM for inhibition of Cdc25A, -B and -C respectively). Displays 125 - 180-fold selectivity over VH1-related dual-specificity phosphatase and protein tyrosine phosphatase 1b. Inhibits carcinoma cell growth and blocks G2/M phase transition in vitro.

Chemical Identifiers

CAS 93718-83-3
Molecular Formula C14H14O4S2
Molecular Weight (g/mol) 310.382
InChI Key MAASHDQFQDDECQ-UHFFFAOYSA-N
Synonym 2,3-bis 2-hydroxyethylthio-1,4-naphthalenedione, 2,3-bis 2-hydroxyethylsulfanyl naphthalene-1,4-dione, 2,3-bis 2-hydroxyethyl sulfanyl naphthalene-1,4-dione, 1,4-naphthalenedione, 2,3-bis 2-hydroxyethyl thio, tocris-1547, lopac-n-1786, d0j1kh, 1, 2,3-bis 2-hydroxyethyl thio, nsc hplc, 2,3-bis 2-hydroxyethylthio naphthalene-1,4-dione
PubChem CID 262093
IUPAC Name 2,3-bis(2-hydroxyethylsulfanyl)naphthalene-1,4-dione
SMILES C1=CC=C2C(=C1)C(=O)C(=C(C2=O)SCCO)SCCO

Specifications

Quantity 10 mg
Formula Weight 310.38
Percent Purity >97%
Chemical Name or Material NSC 95397

Safety and Handling

Recommended Storage Desiccate at -20°C
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