NSMCE2 Monoclonal Antibody (OTI4H9), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA501634

Catalog No. 50-167-2767

Description

MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.

Specifications

• Antigen: NSMCE2
• Classification: Monoclonal
• Concentration: 0.81 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q96MF7
• Gene Symbols: NSMCE2
• Immunogen: Full length human recombit protein of human NSMCE2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI4H9
• Conjugate: Unconjugated
• Gene: NSMCE2
• Gene Alias: C8orf36, MMS21, NSE2, ZMIZ7
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 286053
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid