NSMCE2 Mouse anti-Human, Clone: OTI4A2, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA501632
DescriptionMMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|C8orf36, MMS21, NSE2, ZMIZ7|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
|Full length human recombit protein of human NSMCE2 produced in E.coli.|
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