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NSMCE2 Mouse anti-Human, Clone: OTI6A6, liquid, TrueMAB™
SDP

Catalog No. 501672768
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50-167-2768 100 μL
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Catalog No. 50-167-2768 Supplier OriGene Supplier No. TA501635
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Description

Mouse Monoclonal Antibody

MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.

Specifications

Antigen NSMCE2
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone OTI6A6
Concentration 0.52 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene NSMCE2
Gene Accession No. Q96MF7
Gene Alias C8orf36, MMS21, NSE2, ZMIZ7
Gene Symbols NSMCE2
Host Species Mouse
Immunogen Full length human recombit protein of human NSMCE2 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 286053
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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