NSUN4 Monoclonal Antibody (4G4), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA542532

Catalog No. PIMA542532

Description

Positive Control: MCF-7 cell lysate, 293 cell lysate, mouse testis tissue, human prostate tissue. Subcellular Location: Mitochondrion.

NSUN4 is a 5-methylcytosine rRNA methytransferase that is involved in mitochondiral ribosome assembly. More specifically NSUN4 is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA. This function is independent of MTREFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). NSUN4 is targeted to LSU by MTREFD2/MTERF4 and is involved in the final step in ribosome biogenesis to ensure that SSU and LSU are assembled.

Specifications

• Antigen: NSUN4
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q96CB9, Q9CZ57
• Gene Symbols: NSUN4
• Immunogen: Recombinant protein within human NSUN4 aa 1-384
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 4G4
• Conjugate: Unconjugated
• Gene: NSUN4
• Gene Alias: 2310010O12Rik; 2810405F18Rik; 5-methylcytosine rRNA methyltransferase NSUN4; AI507900; NOL1/NOP2/Sun domain family member 4; NOL1/NOP2/Sun domain family, member 4; NOP2/Sun domain family, member 4; NOP2/Sun RNA methyltransferase family member 4; Nsun4; putative methyltransferase NSUN4; RGD1559652; RP4-603I14.2; SHTAP; Sperm head and tail associated protein
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 387338, 72181
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov