Invitrogen™ NSUN4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531695

Catalog No. PIPA531695

Description

Recommended positive controls: HeLa, HepG2, HCT116, mouse liver, rat liver. Predicted reactivity: Human (99%), Mouse (84%), Rat (81%), Bovine (83%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

NSUN4 is a 5-methylcytosine rRNA methytransferase that is involved in mitochondiral ribosome assembly. More specifically NSUN4 is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA. This function is independent of MTREFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). NSUN4 is targeted to LSU by MTREFD2/MTERF4 and is involved in the final step in ribosome biogenesis to ensure that SSU and LSU are assembled.

Specifications

• Antigen: NSUN4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NSUN4
• Gene Alias: 2310010O12Rik; 2810405F18Rik; 5-methylcytosine rRNA methyltransferase NSUN4; AI507900; NOL1/NOP2/Sun domain family member 4; NOL1/NOP2/Sun domain family, member 4; NOP2/Sun domain family, member 4; NOP2/Sun RNA methyltransferase family member 4; Nsun4; putative methyltransferase NSUN4; RGD1559652; RP4-603I14.2; SHTAP; Sperm head and tail associated protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 298426, 387338, 72181
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96CB9, Q9CZ57
• Gene Symbols: NSUN4
• Immunogen: Recombinant protein encompassing a sequence within the center region of human NSUN4. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG