Invitrogen™ NSUN4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555876

Catalog No. PIPA555876

Description

Immunogen sequence: MAALTLRGVR ELLKRVDLAT VPRRHRYKKK WAATEPKFPA VRLALQNFDM TYSVQFGDLW PSIRVSLLSE QKYGALVNNF AAWDHVSAKL EQLSAKD Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

NSUN4 is a 5-methylcytosine rRNA methytransferase that is involved in mitochondiral ribosome assembly. More specifically NSUN4 is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA. This function is independent of MTREFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). NSUN4 is targeted to LSU by MTREFD2/MTERF4 and is involved in the final step in ribosome biogenesis to ensure that SSU and LSU are assembled.

Specifications

• Antigen: NSUN4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NSUN4
• Gene Alias: 2310010O12Rik; 2810405F18Rik; 5-methylcytosine rRNA methyltransferase NSUN4; AI507900; NOL1/NOP2/Sun domain family member 4; NOL1/NOP2/Sun domain family, member 4; NOP2/Sun domain family, member 4; NOP2/Sun RNA methyltransferase family member 4; Nsun4; putative methyltransferase NSUN4; RGD1559652; RP4-603I14.2; SHTAP; Sperm head and tail associated protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 387338
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96CB9
• Gene Symbols: NSUN4
• Immunogen: Recombinant protein corresponding to Human NSUN4. Recombinant protein control fragment (Product #RP-94123).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG