Invitrogen™ NSUN6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521823

Catalog No. PIPA521823

Description

Recommended positive controls: 293T, HeLaS3, HepG2, Molt-4. Predicted reactivity: Mouse (82%), Rat (81%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

NSun6 is an RNA methyltransferase that catalyzes the methylation at position cytosine C72 in some tRNAs. NSUN6 has been reported to localize to the cytoplasm and largely colocalize with Golgi apparatus and pericentriolar matrix, indicating that NSUN6 modifies tRNAs in a late step in their biogenesis. NSun6 may also play a major role in bone metastasis and could be a valuable therapeutic target for bone metastasis.

Specifications

• Antigen: NSUN6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NSUN6
• Gene Alias: 4933403D21Rik; 4933414E04Rik; ARL5B antisense RNA 1; ARL5B-AS1; NOL1/NOP2/Sun and PUA domain-containing protein 1; NOL1/NOP2/Sun domain family 6; NOL1/NOP2/Sun domain family member 6; NOL1/NOP2/Sun domain family, member 6; NOP2/Sun domain family, member 6; NOP2/Sun RNA methyltransferase family member 6; NOPD1; NSUN6; nucleolar protein (NOL1/NOP2/sun) and PUA domains 1; putative methyltransferase NSUN6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 221078
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.84 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8TEA1
• Gene Symbols: NSUN6
• Immunogen: Recombinant protein encompassing a sequence within the center region of human NSUN6. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG