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Invitrogen™ NSUN6 Polyclonal Antibody
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Catalog No. PIPA596608
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100 μL
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PIPA596608 100 μL
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Catalog No. PIPA596608 Supplier Invitrogen™ Supplier No. PA596608
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NLPSALVSHV LNPQPGEKIL DLCAAPGGKT THIAALMHDQ GEVIALDKIF NKVEKIKQNA LLLGLNSIRA FCFDGTKAVK LDMVEDTEGE PPFLPESFDR ILLDAPCSGM GQRPNMACTW SVKEVASYQP LQRKLFTAAV QLLKPEGVLV YSTCTITLAE NEEQVAWALT KFPCLQLQPQ EPQIGGEGMR GAGLSCEQLK QLQRFDPSAV PLPDTDMDSL REARREDMLR LANKDSIGFF IAKFVKCKST; Positive Samples: Jurkat, HepG2, HeLa, 293T, Mouse testis.

NSun6 is an RNA methyltransferase that catalyzes the methylation at position cytosine C72 in some tRNAs. NSUN6 has been reported to localize to the cytoplasm and largely colocalize with Golgi apparatus and pericentriolar matrix, indicating that NSUN6 modifies tRNAs in a late step in their biogenesis. NSun6 may also play a major role in bone metastasis and could be a valuable therapeutic target for bone metastasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NSUN6
Applications ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 3.32 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NSUN6
Gene Accession No. Q7TS68, Q8TEA1
Gene Alias 4933403D21Rik; 4933414E04Rik; ARL5B antisense RNA 1; ARL5B-AS1; NOL1/NOP2/Sun and PUA domain-containing protein 1; NOL1/NOP2/Sun domain family 6; NOL1/NOP2/Sun domain family member 6; NOL1/NOP2/Sun domain family, member 6; NOP2/Sun domain family, member 6; NOP2/Sun RNA methyltransferase family member 6; NOPD1; NSUN6; nucleolar protein (NOL1/NOP2/sun) and PUA domains 1; putative methyltransferase NSUN6
Gene Symbols NSUN6
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 220-469 of human NSUN6 (NP_8723491).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 221078, 74455
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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