Invitrogen™ NSUN6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596608

Catalog No. PIPA596608

Description

Immunogen sequence: NLPSALVSHV LNPQPGEKIL DLCAAPGGKT THIAALMHDQ GEVIALDKIF NKVEKIKQNA LLLGLNSIRA FCFDGTKAVK LDMVEDTEGE PPFLPESFDR ILLDAPCSGM GQRPNMACTW SVKEVASYQP LQRKLFTAAV QLLKPEGVLV YSTCTITLAE NEEQVAWALT KFPCLQLQPQ EPQIGGEGMR GAGLSCEQLK QLQRFDPSAV PLPDTDMDSL REARREDMLR LANKDSIGFF IAKFVKCKST; Positive Samples: Jurkat, HepG2, HeLa, 293T, Mouse testis.

NSun6 is an RNA methyltransferase that catalyzes the methylation at position cytosine C72 in some tRNAs. NSUN6 has been reported to localize to the cytoplasm and largely colocalize with Golgi apparatus and pericentriolar matrix, indicating that NSUN6 modifies tRNAs in a late step in their biogenesis. NSun6 may also play a major role in bone metastasis and could be a valuable therapeutic target for bone metastasis.

Specifications

• Antigen: NSUN6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NSUN6
• Gene Alias: 4933403D21Rik; 4933414E04Rik; ARL5B antisense RNA 1; ARL5B-AS1; NOL1/NOP2/Sun and PUA domain-containing protein 1; NOL1/NOP2/Sun domain family 6; NOL1/NOP2/Sun domain family member 6; NOL1/NOP2/Sun domain family, member 6; NOP2/Sun domain family, member 6; NOP2/Sun RNA methyltransferase family member 6; NOPD1; NSUN6; nucleolar protein (NOL1/NOP2/sun) and PUA domains 1; putative methyltransferase NSUN6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 221078, 74455
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 3.32 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q7TS68, Q8TEA1
• Gene Symbols: NSUN6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-469 of human NSUN6 (NP_8723491).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG