Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ NTAL Monoclonal Antibody (NAP-03)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA119327

Catalog No. 01-676-083


Only null left
Add to Cart

Description

Description

This antibody recognizes a defined intracellular epitope (aa 196-212) of human Non-T cell Activation Linker (NTAL), also known as LAB (linker of activated B cells), a 30 kDa transmembrane adaptor protein associating with lipid raft components in the plasma membrane of B cells, NK cells and myeloid cells. This antibody will not cross-react with mouse. Western Blot: Incubation 60 min; non-reducing conditions, 12% separating SDS-PAGE gel.

NTAL (Non-T cell Activation Linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NTAL
Monoclonal
1 mg/mL
PBS with 15 mM sodium azide; pH 7.4
Q9GZY6
LAT2
Peptide corresponding to aa 196-212 of human NTAL, coupled to KLH.
100 μg
Primary
Human
Antibody
IgG2a
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
NAP-03
Unconjugated
LAT2
AW125574; HSPC046; LAB; Lat2; LAT-2 like; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T cells, transmembrane adaptor 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; non-T cell activation linker; non-T-cell activation linker; NTAL; WBS15; WBSCR15; WBSCR5; Williams-Beuren syndrome chromosomal region 15 protein; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosomal region 5 protein; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5-like protein; WSCR5
Mouse
Protein A
RUO
7462
4°C, do not freeze
Liquid
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.