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Invitrogen™ NTE Polyclonal Antibody

Catalog No. PIPA535939
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PIPA535939 100 μL
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Catalog No. PIPA535939 Supplier Invitrogen™ Supplier No. PA535939
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Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG, SK-N-SH, IMR-32, SK-N-AS, rat brain. Predicted reactivity: Mouse (99%), Chicken (94%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NTE
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene pnpla6
Gene Accession No. Q3TRM4, Q8IY17
Gene Alias 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI661849; BNHS; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; iPLA2delta; LNMS; MSws; Neuropathy target esterase; NT; NT5; NT5E; NTE; NTEMND; OMCS; patatin like phospholipase domain containing 6; patatin-like phospholipase domain containing 6; patatin-like phospholipase domain-containing protein 6; PNPLA6; Purine 5-Prime-Nucleotidase; RGD1564611; SPG39; Swiss cheese; Swiss-cheese; sws; wu:fy20f06
Gene Symbols pnpla6
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human NTE. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10908, 360753, 50767
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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