Invitrogen™ NTE Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA535939

Catalog No. PIPA535939

Description

Recommended positive controls: U87-MG, SK-N-SH, IMR-32, SK-N-AS, rat brain. Predicted reactivity: Mouse (99%), Chicken (94%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NTE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: pnpla6
• Gene Alias: 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI661849; BNHS; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; iPLA2delta; LNMS; MSws; Neuropathy target esterase; NT; NT5; NT5E; NTE; NTEMND; OMCS; patatin like phospholipase domain containing 6; patatin-like phospholipase domain containing 6; patatin-like phospholipase domain-containing protein 6; PNPLA6; Purine 5-Prime-Nucleotidase; RGD1564611; SPG39; Swiss cheese; Swiss-cheese; sws; wu:fy20f06
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10908, 360753, 50767
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.4 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q3TRM4, Q8IY17
• Gene Symbols: pnpla6
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human NTE. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG