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Invitrogen™ NTN3 Polyclonal Antibody
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Catalog No. PIPA562249
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PIPA562249 100 μL
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Catalog No. PIPA562249 Supplier Invitrogen™ Supplier No. PA562249
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CVPGLVNAAL GREVLASSTC GRPATRACDA SDPRRAHSPA LLTSPGGTAS PLCWRSESLP RAPLNVTLTV PLGKAFELVF V Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 83%.

Netrin-3 (NTN3) is a gene located on chromosome 16q22.1, encoding a protein that belongs to the netrin family of secreted molecules crucial for axon guidance and cell signaling in nervous system development. NTN3 is primarily expressed in the central nervous system, where it functions as a guidance cue for developing neurons, influencing processes such as axon attraction or repulsion and the establishment of neural networks. The protein interacts with specific receptors on neuronal growth cones to mediate directional movement and synapse formation. Beyond its role in neural development, NTN3 is involved in tissue morphogenesis and cellular migration in other physiological contexts. Aberrant expression or mutations in NTN3 can lead to developmental disorders and neurodegenerative conditions due to impaired neural pathway formation. Research into NTN3 continues to explore its therapeutic potential for enhancing neural repair and regeneration in pathological states.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NTN3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NTN3
Gene Accession No. O00634
Gene Alias netrin 1; netrin 3; netrin-2; Netrin-2, chicken, homolog of, like; netrin-2-like protein; Netrin-3; NTN1; NTN2; NTN2L; Ntn3
Gene Symbols NTN3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NTN3. Recombinant protein control fragment (Product #RP-98705).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4917
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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