NTRK1 Mouse anti-Human, Clone: OTI5B6, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF806413

Catalog No. 50-166-7831

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TrkA (tropomyosin receptor kinase A) encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Specifications

• Antigen: NTRK1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: NTRK1
• Gene Alias: MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4914
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI5B6
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P04629
• Gene Symbols: NTRK1
• Immunogen: Human recombit protein fragment corresponding to amino acids 440-796 of human NTRK1 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1