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NTRK1 (phospho Y701) Rabbit anti-Human, Mouse, Rat, Polyclonal , Abnova™

Catalog No. 89956776 Shop All Abnova Corporation Products
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89-956-776 100 μL
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Catalog No. 89-956-776 Supplier Abnova Corporation Supplier No. PAB29637
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Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NTRK1.

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq]

Specifications

Antigen NTRK1 (phospho Y701)
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NTRK1.
Dilution Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:3000) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Alias DKFZp781I14186/MTC/TRK/TRK1/TRKA/p140-TrkA
Gene Symbols NTRK1
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y701 of human NTRK1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4914
Test Specificity NTRK1 (phospho Y701) polyclonal antibody detects endogenous levels of human NTRK1 only when phosphorylated at tyrosine 701.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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