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NTRK1 (phospho Y701) Rabbit anti-Human, Mouse, Rat, Polyclonal , Abnova™
Shop All Abnova Corporation ProductsDescription
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq]
Specifications
Specifications
| Antigen | NTRK1 (phospho Y701) |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NTRK1. |
| Dilution | Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:3000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Gene Alias | DKFZp781I14186/MTC/TRK/TRK1/TRKA/p140-TrkA |
| Gene Symbols | NTRK1 |
| Host Species | Rabbit |
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