NTRK3 Mouse anti-Human, Clone: OTI4E10, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF500538

Catalog No. 50-165-9608

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TRKC, a member of the insulin receptor subfamily of tyrosine protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.

Specifications

• Antigen: NTRK3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: NTRK3
• Gene Alias: GP145-TrkC, TRKC, gp145(trkC)
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4916
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4E10
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q16288
• Gene Symbols: NTRK3
• Immunogen: Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1