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NTRK3 Mouse anti-Human, Clone: OTI4E10, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF500538

Encompass_Preferred

Catalog No. 50-165-9608


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TRKC, a member of the insulin receptor subfamily of tyrosine protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
Specifications

Specifications

NTRK3
Monoclonal
Unconjugated
NTRK3
GP145-TrkC, TRKC, gp145(trkC)
Mouse
Affinity Chromatography
RUO
4916
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI4E10
PBS with 8% trehalose and no preservative; pH 7.3
Q16288
NTRK3
Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector
100 μg
Primary
Human
Antibody
IgG1
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