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Invitrogen™ NTSR2 Polyclonal Antibody
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Catalog No. APS300
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100 μL
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APS300 100 μL
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Catalog No. APS300 Supplier Invitrogen™ Supplier No. PA3300
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Rabbit Polyclonal Antibody

PA3-300 detects neurotensin receptor NTS2 from human samples. PA3-300 has been successfully used in Western blot and immunohistochemistry (paraffin) procedures. By Western blot this antibody detects a ~55-60 kDa protein representing NTS2 receptor. The PA3-300 immunogen is a synthetic peptide corresponding to residues P(381) Q S P T L M D T A S G F G D P P E T R T(401) of human NTS2 receptor.

The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NTSR2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with 0.05% sodium azide
Gene NTSR2
Gene Accession No. O95665
Gene Alias High-affinity levocabastine-sensitive neurotensin receptor; levocabastine-sensitive neurotensin receptor; low affinity neurotensin receptor; low-affinity levocabastine-sensitive neurotensin receptor; neurotensin receptor 2; neurotensin receptor type 2; neurotensin receptor, type 2; NT2 receptor; NT2R; NTR2; NT-R-2; NTR2 receptor; NTRL; Ntsr2
Gene Symbols NTSR2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues P(381) Q S P T L M D T A S G F G D P P E T R T(401) of human NTS2 receptor.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23620
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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