Invitrogen™ NTSR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532952

Catalog No. PIPA532952

Description

Percent identity with other species by BLAST analysis: Human, Gibbon, Marmoset (100%); Monkey, Mouse, Rat, Bovine, Rabbit (94%); Dog, Hamster, Panda, Pig (88%). Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.

The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.

Specifications

• Antigen: NTSR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NTSR2
• Gene Alias: High-affinity levocabastine-sensitive neurotensin receptor; levocabastine-sensitive neurotensin receptor; low affinity neurotensin receptor; low-affinity levocabastine-sensitive neurotensin receptor; neurotensin receptor 2; neurotensin receptor type 2; neurotensin receptor, type 2; NT2 receptor; NT2R; NTR2; NT-R-2; NTR2 receptor; NTRL; Ntsr2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23620
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: O95665
• Gene Symbols: NTSR2
• Immunogen: Synthetic 16 amino acid peptide from internal region of human NTSR2.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov