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Invitrogen™ NTSR2 Polyclonal Antibody
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Catalog No. PIPA532953
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50 μg
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PIPA532953 50 μg
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Catalog No. PIPA532953 Supplier Invitrogen™ Supplier No. PA532953
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gibbon (100%); Monkey, Bovine, Dog, Pig (95%); Marmoset, Mouse, Rat (90%); Hamster (85%); Rabbit (80%). For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NTSR2
Applications ELISA, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene NTSR2
Gene Accession No. O95665
Gene Alias High-affinity levocabastine-sensitive neurotensin receptor; levocabastine-sensitive neurotensin receptor; low affinity neurotensin receptor; low-affinity levocabastine-sensitive neurotensin receptor; neurotensin receptor 2; neurotensin receptor type 2; neurotensin receptor, type 2; NT2 receptor; NT2R; NTR2; NT-R-2; NTR2 receptor; NTRL; Ntsr2
Gene Symbols NTSR2
Host Species Rabbit
Immunogen Synthetic 20 amino acid peptide from internal region of human NTSR2.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23620
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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