Invitrogen™ NUCB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579767

Catalog No. PIPA579767

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: HEPA whole cell. IHC: mouse gaster tissue, rat gaster tissue.

NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.

Specifications

• Antigen: NUCB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NUCB2
• Gene Alias: AI607786; Calnuc; DNA-binding protein NEFA; epididymis secretory protein Li 109; Gastric cancer antigen Zg4; HEL-S-109; LOW QUALITY PROTEIN: nucleobindin-2; NEFA; nesfatin 1; nesfatin-1; Nucb2; nucleobindin 2; nucleobindin-2; Nucleobindin-2/Nesfatin-1; nucleobindin-2-like protein; nucleobinding 2; p54; prepronefastin; prepronesfatin
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 53322, 59295
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: P81117, Q9JI85
• Gene Symbols: NUCB2
• Immunogen: E. coli-derived mouse Nucleobindin 2 recombinant protein (Position: V25-L106).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG