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Invitrogen™ NUCB2 Polyclonal Antibody
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Catalog No. PIPA588675
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PIPA588675 100 μL
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Catalog No. PIPA588675 Supplier Invitrogen™ Supplier No. PA588675
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Rabbit Polyclonal Antibody

Immunogen sequence: ATEKKEFLEP DSWETLDQQQ FFTEEELKEY ENIIALQENE LKKKADELQK QKEELQRQHD QLEAQKLEYH QVIQQMEQKK LQQGIPPSGP AGELKFEPHI; Positive Samples: LO2, HeLa, Jurkat, SGC-7901; Cellular Location: Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Membrane, Nucleus envelope, Peripheral membrane protein.

NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NUCB2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene NUCB2
Gene Accession No. P80303, Q9JI85
Gene Alias AI607786; Calnuc; DNA-binding protein NEFA; epididymis secretory protein Li 109; Gastric cancer antigen Zg4; HEL-S-109; LOW QUALITY PROTEIN: nucleobindin-2; NEFA; nesfatin 1; nesfatin-1; Nucb2; nucleobindin 2; nucleobindin-2; Nucleobindin-2/Nesfatin-1; nucleobindin-2-like protein; nucleobinding 2; p54; prepronefastin; prepronesfatin
Gene Symbols NUCB2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 321-420 of human NUCB2 (NP_0050041).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4925, 59295
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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