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Invitrogen™ NUCB2 Polyclonal Antibody
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Catalog No. PIPA541311
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100 μL
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PIPA541311 100 μL
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Catalog No. PIPA541311 Supplier Invitrogen™ Supplier No. PA541311
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Rabbit Polyclonal Antibody

Peptide sequence: MMKEHERREY LKTLNEEKRK EEESKFEEMK KKHENHPKVN HPGSKDQLKE Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 93%; Yeast: 91%.

NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NUCB2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene NUCB2
Gene Accession No. P80303, P81117
Gene Alias AI607786; Calnuc; DNA-binding protein NEFA; epididymis secretory protein Li 109; Gastric cancer antigen Zg4; HEL-S-109; LOW QUALITY PROTEIN: nucleobindin-2; NEFA; nesfatin 1; nesfatin-1; Nucb2; nucleobindin 2; nucleobindin-2; Nucleobindin-2/Nesfatin-1; nucleobindin-2-like protein; nucleobinding 2; p54; prepronefastin; prepronesfatin
Gene Symbols NUCB2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human NUCB2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4925, 53322
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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