NUCB2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA534526

Catalog No. PIPA534526

Description

A suggested positive control is rat brain tissue lysate. PA5-34526 can be used with blocking peptide PEP-1569.

NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.

Specifications

• Antigen: NUCB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NUCB2
• Gene Alias: AI607786; Calnuc; DNA-binding protein NEFA; epididymis secretory protein Li 109; Gastric cancer antigen Zg4; HEL-S-109; LOW QUALITY PROTEIN: nucleobindin-2; NEFA; nesfatin 1; nesfatin-1; Nucb2; nucleobindin 2; nucleobindin-2; Nucleobindin-2/Nesfatin-1; nucleobindin-2-like protein; nucleobinding 2; p54; prepronefastin; prepronesfatin
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4925, 53322, 59295
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P80303, P81117, Q9JI85
• Gene Symbols: NUCB2
• Immunogen: A 16 amino acid peptide near the center of human Nucleobindin-2
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov