Invitrogen™ Nudel Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596422

Catalog No. PIPA596422

Description

Immunogen sequence: MDGEDIPDFS SLKEETAYWK ELSLKYKQSF QEARDELVEF QEGSRELEAE LEAQLVQAEQ RNRDLQADNQ RLKYEVEALK EKLEHQYAQS YKQVSVLEDD LSQTRAIKEQ LHKYVRELEQ ANDDLERAKR ATIVSLEDFE QRLNQAIERN AFLESELDEK ESLLVSVQRL KDEARDLRQE LAVRERQQEV TRKSAPSSPT LDCEKMDSAV QASLSLPATP VGKGTENTFP SPKAIPNGFG TSPLTPSARI SALNIVGDLL RKVGALESKL AACRNFAKDQ ASRKSYISGN VNCGVLNGNG TKFSRSGHTS FFDKGAVNGF DPAPPPPGLG SSRPSSAPGM LPLSV; Positive Samples: U-87MG, Mouse brain; Cellular Location: Chromosome, Cytoplasm, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, spindle.

This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: Nudel
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ndel1
• Gene Alias: 2600006O07Rik; ATP-sensitive inward rectifier potassium channel 15; DKFZp451M0318; endooligopeptidase A; EOPA; Inward rectifier K(+) channel Kir4.2; Kcnj15; Kir4.2; LIS1-interacting protein NUDEL; LIS1-interacting protein NUDEL; endooligopeptidase A; MITAP1; Mitosin-associated protein 1; mitosin-associated protein MITAP1; mNudel; mNudE-L; NDE1L1; NDE2; Ndel1; nuclear disribution gene E like; nuclear distribution gene E-like homolog 1; nuclear distribution gene E-like homolog 1 (A. nidulans); nuclear distribution protein nudE-like 1; nudE neurodevelopment protein 1 like 1; nudE neurodevelopment protein 1-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog like 1; nudE nuclear distribution gene E homolog-like 1; Nude2; NUDEL; NUDE-like protein; Potassium channel, inwardly rectifying subfamily J member 15; potassium channel, inwardly rectifying subfamily J, member 15; potassium inwardly-rectifying channel, subfamily J, member 15; Protein mNudE-like; Protein Nudel; unnamed protein product
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81565, 83431
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.73 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9ERR1, Q9GZM8
• Gene Symbols: Ndel1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-345 of human NUDEL/NUDEL/NDEL1 (NP_1104351).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG