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Invitrogen™ NUDT2 Polyclonal Antibody
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Catalog No. PIPA5117075
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100 μL
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PIPA5117075 100 μL
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Catalog No. PIPA5117075 Supplier Invitrogen™ Supplier No. PA5117075
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Description

Rabbit Polyclonal Antibody

Positive Samples: SKOV3, HL-60, Mouse kidney, Mouse heart, Mouse brain, Mouse liver, Rat kidney, Rat heart Immunogen sequence: MALRACGLII FRRCLIPKVD NNAIEFLLLQ ASDGIHHWTP PKGHVEPGED DLETALRETQ EEAGIEAGQL TIIEGFKREL NYVARNKPKT VIYWLAEVKD YDVEIRLSHE HQAYRWLGLE EACQLAQFKE MKAALQEGHQ FLCSIEA.

This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NUDT2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NUDT2
Gene Accession No. P50583, P56380, Q6PEC0
Gene Alias 2310051L06Rik; AA939917; Ap4A hydrolase; Ap4A hydrolase 1; Ap4Aase; APAH1; bis(5'-nucleosyl)-tetraphosphatase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; diadenosine tetraphosphatase; MGC10404; nucleoside diphosphate-linked moiety X motif 2; nudix (nucleoside diphosphate linked moiety X)-type motif 2; nudix hydrolase 2; nudix motif 2; Nudt2
Gene Symbols NUDT2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human NUDT2 (NP_0011521).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 297998, 318, 66401
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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