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Invitrogen™ NUDT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5117075

Catalog No. PIPA5117075


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Description

Description

Positive Samples: SKOV3, HL-60, Mouse kidney, Mouse heart, Mouse brain, Mouse liver, Rat kidney, Rat heart Immunogen sequence: MALRACGLII FRRCLIPKVD NNAIEFLLLQ ASDGIHHWTP PKGHVEPGED DLETALRETQ EEAGIEAGQL TIIEGFKREL NYVARNKPKT VIYWLAEVKD YDVEIRLSHE HQAYRWLGLE EACQLAQFKE MKAALQEGHQ FLCSIEA.

This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NUDT2
Polyclonal
Unconjugated
NUDT2
2310051L06Rik; AA939917; Ap4A hydrolase; Ap4A hydrolase 1; Ap4Aase; APAH1; bis(5'-nucleosyl)-tetraphosphatase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; diadenosine tetraphosphatase; MGC10404; nucleoside diphosphate-linked moiety X motif 2; nudix (nucleoside diphosphate linked moiety X)-type motif 2; nudix hydrolase 2; nudix motif 2; Nudt2
Rabbit
Affinity Chromatography
RUO
297998, 318, 66401
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
0.37 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P50583, P56380, Q6PEC0
NUDT2
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human NUDT2 (NP_0011521).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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