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Invitrogen™ NUDT2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5117075
Description
Positive Samples: SKOV3, HL-60, Mouse kidney, Mouse heart, Mouse brain, Mouse liver, Rat kidney, Rat heart Immunogen sequence: MALRACGLII FRRCLIPKVD NNAIEFLLLQ ASDGIHHWTP PKGHVEPGED DLETALRETQ EEAGIEAGQL TIIEGFKREL NYVARNKPKT VIYWLAEVKD YDVEIRLSHE HQAYRWLGLE EACQLAQFKE MKAALQEGHQ FLCSIEA.
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.
Specifications
NUDT2 | |
Polyclonal | |
Unconjugated | |
NUDT2 | |
2310051L06Rik; AA939917; Ap4A hydrolase; Ap4A hydrolase 1; Ap4Aase; APAH1; bis(5'-nucleosyl)-tetraphosphatase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; diadenosine tetraphosphatase; MGC10404; nucleoside diphosphate-linked moiety X motif 2; nudix (nucleoside diphosphate linked moiety X)-type motif 2; nudix hydrolase 2; nudix motif 2; Nudt2 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
297998, 318, 66401 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
0.37 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P50583, P56380, Q6PEC0 | |
NUDT2 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human NUDT2 (NP_0011521). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
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