Invitrogen™ NUDT5 Recombinant Rabbit Monoclonal Antibody (10D2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA550039

Catalog No. FEMA550039

Description

NUDT5 Recombinant Monoclonal Antibody for Western Blot, Flow, ELISA

Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate. In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.

Specifications

• Antigen: NUDT5
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9UKK9
• Gene Symbols: NUDT5
• Immunogen: A synthesized peptide derived from human NUDT5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 10D2
• Conjugate: Unconjugated
• Gene: NUDT5
• Gene Alias: 8-oxo-dGDP phosphatase; ADP-sugar pyrophosphatase; HSPC115; Nuclear ATP-synthesis protein NUDIX5; Nucleoside diphosphate-linked moiety X motif 5; nudix (nucleoside diphosphate linked moiety X)-type motif 5; nudix hydrolase 5; nudix motif 5; NUDIX5; nudix-type motif 5; NUDT5; YSA1; YSA1H; YSAH1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11164
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid