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Invitrogen™ NUDT5 Recombinant Rabbit Monoclonal Antibody (JE56-41)
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Catalog No. PIMA544905
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100 μL
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PIMA544905 100 μL
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Catalog No. PIMA544905 Supplier Invitrogen™ Supplier No. MA544905
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Rabbit Recombinant Monoclonal Antibody

NUDT5 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate. In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NUDT5
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JE56-41
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene NUDT5
Gene Accession No. Q9UKK9
Gene Alias 8-oxo-dGDP phosphatase; ADP-sugar pyrophosphatase; HSPC115; Nuclear ATP-synthesis protein NUDIX5; Nucleoside diphosphate-linked moiety X motif 5; nudix (nucleoside diphosphate linked moiety X)-type motif 5; nudix hydrolase 5; nudix motif 5; NUDIX5; nudix-type motif 5; NUDT5; YSA1; YSA1H; YSAH1
Gene Symbols NUDT5
Host Species Rabbit
Immunogen Recombinant protein within human NUDT5 aa 1-150.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11164
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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