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NUMB Mouse anti-Human, Clone: OTI2F1, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF802163

Encompass_Preferred

Catalog No. 50-166-5885


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.
Specifications

Specifications

NUMB
Monoclonal
Unconjugated
NUMB
C14orf41, S171, c14_5527
Mouse
Affinity Chromatography
RUO
8650
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI2F1
PBS with 8% trehalose and no preservative; pH 7.3
P49757
NUMB
Human recombit protein fragment corresponding to amino acids 1-365 of human NUMB produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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