NUMB Mouse anti-Human, Clone: OTI5A9, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA501561S
DescriptionProtein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|C14orf41, S171, c14_5527|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of human NUMB produced in HEK293T cell.|
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