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NUMB Mouse anti-Human, Clone: OTI5A9, liquid, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA501561

Encompass_Preferred

Catalog No. 50-167-2697


May include imposed supplier surcharges.
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Description

Description

Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.
Specifications

Specifications

NUMB
Monoclonal
0.58 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P49757
NUMB
Full length human recombit protein of human NUMB produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG1
Immunohistochemistry (Paraffin), Western Blot
OTI5A9
Unconjugated
NUMB
C14orf41, S171, c14_5527
Mouse
Affinity Chromatography
RUO
8650
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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