NUMBL Monoclonal Antibody (OTI8D2), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-4451	100 μL

Catalog No. 50-168-4451 Supplier OriGene Supplier No. TA812202

Description

Mouse Monoclonal Antibody

The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, including Eps15, LNX1 and Notch 1. NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate. Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1. In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.

Specifications

• Antigen: NUMBL
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI8D2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: NUMBL
• Gene Accession No.: Q9Y6R0
• Gene Alias: CAG3A, CTG3a, NBL, NUMB-R, NUMBLIKE, NUMBR, TNRC23
• Gene Symbols: NUMBL
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-225 of human NUMBL produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9253
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1