Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA563564

Invitrogen™ NUMBL Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA563564
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA563564 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA563564 Supplier Invitrogen™ Supplier No. PA563564
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: NELPSTLQRR TDFQVKGTVP EMEPPGAGDS DSINALCTQI SSSFASAGAP Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 94%.

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen NUMBL
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Numbl
Gene Accession No. Q9Y6R0
Gene Alias CAG3A; CTG3a; NBL; numb homolog (Drosophila)-like; numb homolog-like; NUMB like, endocytic adaptor protein; Numbl; NUMBLIKE; numb-like; numb-like protein; NUMBR; Numb-R; numb-related protein; TNRC23
Gene Symbols Numbl
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NUMBL. Recombinant protein control fragment (Product #RP-98382).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9253
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.