NUP160 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-8061	100 μL

Catalog No. 50-198-8061 Supplier Bioss Supplier No. BS7843R

Description

Rabbit Polyclonal Antibody

The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment. Multiple isoforms of NUP160 are known to exist.

Specifications

• Antigen: NUP160
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: NUP160
• Gene Accession No.: Q12769
• Gene Alias: 160 kDa nucleoporin; 160kDa; 2810011M03Rik; AA414952; AU020188; Gene trap locus 1-13 protein; gene trap locus-13; Gtl1-13; Gtl13; GTL-13; KIAA0197; mKIAA0197; Nuclear pore complex protein Nup160; nucleoporin 160; nucleoporin 160kD; nucleoporin 160kDa; Nucleoporin Nup160; NUP120; NUP160
• Gene Symbols: NUP160
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human NUP160.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 23279
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG