Invitrogen™ NUP214 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5111282

Catalog No. PIPA5111282

Description

Immunogen sequence: FDSPEELPKE RSSLLAVSNK YGLVFAGGAS GLQIFPTKNL LIQNKPGDDP NKIVDKVQGL LVPMKFPIHH LALSCDNLTL SACMMSSEY.

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: NUP214
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NUP214
• Gene Alias: 214 kDa nucleoporin; BC039282; CAIN; CAN; CAN protein, putative oncogene; D2H9S46E; Kiaa0023; Nuclear pore complex protein Nup214; nucleoporin 214; nucleoporin 214kDa; nucleoporin Nup214; Nup214; Protein CAN; RGD1304977
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8021
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P35658
• Gene Symbols: NUP214
• Immunogen: Recombinant Protein corresonding to Human NUP214. Recombinant protein control fragment (Product #RP-106203).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov