Invitrogen™ NUP214 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114371

Catalog No. PIPA5114371

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human HEK293 whole cell, human K562 whole cell, human THP-1 whole cell, mouse spleen tissue, mouse thymus tissue. ICC/IF: A431 cell, NIH/3T3 cell. Flow: HL-60 cell, HEPA1-6 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: NUP214
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NUP214
• Gene Alias: 214 kDa nucleoporin; BC039282; CAIN; CAN; CAN protein, putative oncogene; D2H9S46E; Kiaa0023; Nuclear pore complex protein Nup214; nucleoporin 214; nucleoporin 214kDa; nucleoporin Nup214; Nup214; Protein CAN; RGD1304977
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 227720, 8021
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P35658, Q80U93
• Gene Symbols: NUP214
• Immunogen: E.coli-derived human NUP214 recombinant protein (Position: K36-E374).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov