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Invitrogen™ NUP214 Polyclonal Antibody
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Catalog No. PIPA5115679
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PIPA5115679 100 μL
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Catalog No. PIPA5115679 Supplier Invitrogen™ Supplier No. PA5115679
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NUP214.

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NUP214
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene NUP214
Gene Accession No. P35658, Q80U93
Gene Alias 214 kDa nucleoporin; BC039282; CAIN; CAN; CAN protein, putative oncogene; D2H9S46E; Kiaa0023; Nuclear pore complex protein Nup214; nucleoporin 214; nucleoporin 214kDa; nucleoporin Nup214; Nup214; Protein CAN; RGD1304977
Gene Symbols NUP214
Host Species Rabbit
Immunogen A synthesized peptide derived from human NUP214(Accession P35658), corresponding to amino acid residues P1974-F2024.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 227720, 8021
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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