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  5. R&D Systems™ Nutlin 3a

R&D Systems™ Nutlin 3a
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Catalog No. 60755 Shop All Novus Products
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60-755 5 mg
60-752-5 25 mg
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Catalog No. 60-755 Supplier R&D Systems™ Supplier No. 6075/5

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Description

A Tocris product, part of R&D Systems. MDM2 antagonist; active enantiomer of Nutlin-3 (Cat. No. 3984)

Nutlin 3a is an MDM2 antagonist (IC50 = 90 nM); inhibits the MDM2-p53 interaction. Active enantiomer of Nutlin-3 (Cat. No. 3984). Induces expression for P53 regulated genes. Suppresses tumor growth in vivo >98% in prostate cancer and osteosarcoma cancer models. Antiproliferative.

Specifications

Chemical Name or Material 4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone
CAS 675576-98-4
Assay Percent Range >97%
Quantity 5 mg
Product Line Tocris
Molecular Formula C30H30Cl2N4O4
Formula Weight Observed MW: 581.49
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