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Tocris Bioscience™ NVP 2

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Quantity:
5 mg
Description
NVP 2 is a potent and selective ATP-competitive CDK9 inhibitor (IC50 = 0.5 nM). Exhibits selectivity for CDK9 over a panel of 468 kinases, but inhibits DYRK1B (IC50 = 350 nM), displays <90% binding to CDK7 (IC50 >10 μM) and CDK13. Inhibits proliferation of MOLT4 cells in vitro. Induces apoptosis.
Specifications
Specifications
Chemical Name or Material | 4-[[[5'-Chloro-2'-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino][2,4'-bipyridin]-6-yl]amino]methyl]tetrahydro-2H-pyran-4-carbonitrile |
CAS | 1263373-43-8 |
Quantity | 5 mg |
Molecular Formula | C27H37ClN6O2 |
Formula Weight | 513.07 |
Product Type | Inhibitor |
Purity | 97% |
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