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  5. Tocris Bioscience™ NVP ADW 742

Tocris Bioscience™ NVP ADW 742
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Catalog No. 524710
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52-471-0 10 mg
52-475-0 50 mg
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Description

ATP-competitive inhibitor of IGF1R

NVP ADW 742 is an ATP-competitive inhibitor of IGF1R (IC50 in the range of 0.1-0.2 μM). Also inhibits c-Kit kinase activity (IC50 in the range of 3-5 μM). Exhibits a synergistic effect with Imatinib (Cat. No. 5906), enhancing the sensitivity of multiple small cell lung cancer cell lines to the chemotherapeutics Etoposide (Cat. No. 1226) and Carboplatin (Cat. No. 2626).

Specifications

Quantity 10 mg
Product Type NVP ADW 742
Purity >99%
Molecular Weight (g/mol) 453.58
Inhibitors NVP ADW 742

For Research Use Only

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