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  5. Tocris Bioscience™ NVS PAK1 1

Tocris Bioscience™ NVS PAK1 1
GREENER_CHOICE

Catalog No. 613225
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective PAK1 inhibitor

NVS PAK1 1 is a potent and selective PAK1 inhibitor (IC50 = 5 nM) that displays selective for PAK1 over PAK2 and a panel of 442 kinases. NVS PAK1 1 inhibits autophosphorylation of PAK1 in KRAS-mutated pancreatic cancer cell lines.

A negative control for NVS PAK1 1 is also available; NVS PAK1 C .

Specifications

Chemical Name or Material (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N-isopropylpyrrolidine-1-carboxamide
CAS 1783816-74-9
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C23H25ClF3N5O
Formula Weight Observed MW: 479.93
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