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Tocris Bioscience™ NVS-STG2
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Catalog No. 812010
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81-201-0 10 mg
81-205-0 50 mg
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Catalog No. 81-201-0 Supplier Tocris Bioscience™ Supplier No. 8120/10
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STING agonist, molecular glue that causes oligomerization of STING

NVS-STG2 is a STING agonist. It induces oligomerization of human STING by binding to pockets between adjacent STING dimer transmembrane domains, acting as a molecular glue. NVS-STG2 elicits potent STING-mediated immune responses in cells and produces antitumor activities in hSTING knock-in mice.

Specifications

Chemical Name or Material 4-((4-(2-(tert-Butyl)-5,5-dimethyl-1,3-dioxan-2-yl)benzyl)amino)-3-methoxybenzoic acid
CAS 3030588-01-0
Quantity 10 mg
Target STING Agonists
Molecular Formula C25H33NO5
Purity 0.98
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