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Invitrogen™ NY-BR-1 Polyclonal Antibody
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Catalog No. PIPA5101251
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100 μL
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PIPA5101251 100 μL
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Catalog No. PIPA5101251 Supplier Invitrogen™ Supplier No. PA5101251
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total AN30A.

NY-BR-1 is a novel differentiation marker predominantly expressed in normal breast and breast cancer. It has been shown by Immunohistochemistry (IHC) that NY-BR-1 was present solely in ductal epithelium of normal breast tissue. Invasive carcinoma of the breast and carcinoma in situ were positive for NY-BR-1, whereas most other tumors and normal tissues are negative, with the exceptions of one-third of sweat gland carcinomas and around two percent of prostate carcinoma. NY-BR-1 is reported to express more frequently in estrogen-positive and lymph node-negative primary carcinomas, and more commonly in grade 1 than in grade 2 or grade 3. In a study by Varga et al (2006) forty-nine percent of lymph node metastasis were shown to be positive.
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Specifications

Antigen NY-BR-1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ANKRD30A
Gene Accession No. Q9BXX3
Gene Alias ANKRD30A; ankyrin repeat domain 30A; ankyrin repeat domain-containing protein 30A; breast cancer antigen NY-BR-1; NY-BR-1; serologically defined breast cancer antigen NY-BR-1
Gene Symbols ANKRD30A
Host Species Rabbit
Immunogen A synthesized peptide derived from human ANKRD30A(Accession Q9BXX3), corresponding to amino acid residues H1102-L1152.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 91074
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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