Invitrogen™ NY-ESO-1 Monoclonal Antibody (E978)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 356200

Catalog No. 35-620-0

Description

This antibody can react specifically with the 23 kDa NY-ESO-1 protein. During development reactivity was confirmed with human SKMEL-37 melanoma cells.

NY-ESO-1, a member of the CT (cancer/testis) family, is a tumor specific shared antigen with distinctive immunogenicity. The molecular basis of T cell-mediated antitumor immunity has been elucidated by the identification of a number of tumor antigens recognized by CD8+ T cells. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen. The NY-ESO-1 has been detected in normal testis and in a range of human tumor types. NY-ESO-1 reactivity in testis is restricted germ cells, particularly in the spermatogonia.

Specifications

• Antigen: NY-ESO-1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene Accession No.: P78358
• Gene Symbols: CTAG1A
• Immunogen: Human NY-ESO-1 recombinant protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: E978
• Conjugate: Unconjugated
• Gene: CTAG1A
• Gene Alias: Autoimmunogenic cancer/testis antigen NY-ESO-1; cancer/testis antigen 1; cancer/testis antigen 1A; cancer/testis antigen 1-A; cancer/testis antigen 6.1; CT6.1; CTAG; CTAG1; CTAG1A; CTAG1B; ESO1; l antigen family member 2; LAGE2; LAGE-2; LAGE2A; LAGE2B; New York Esophageal Squamous Cell Carcinoma 1; NY-ESO-1
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 246100
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid