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Invitrogen™ NYX Polyclonal Antibody
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Catalog No. PIPA5121143
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100 μL
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PIPA5121143 100 μL
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Catalog No. PIPA5121143 Supplier Invitrogen™ Supplier No. PA5121143
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Rabbit Polyclonal Antibody

Positive test controls include: 293T. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space. Immunogen sequence: LLYLDRNSIA FVEEGAFQNL SGLLALHLNG NRLTVLAWVA FQPGFFLGRL FLFRNPWCCD CRLEWLRDWM EGSGRVTDVP CASPGSVAGL DLSQVTFGRS SDGLCVDPEE LNLTTSSPGP SPEPAATTVS RFSSLLSKLL APRVPVEEAA NTTGGLANAS LSDSLSSRGV GGAGRQPWFL LASCLLPSVA QHVVFGLQMD.

The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NYX
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2.95 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NYX
Gene Accession No. P83503, Q9GZU5
Gene Alias CLNP; CLRP; CSNB1; CSNB1A; CSNB4; leucine-rich repeat protein; NBM1; no b wave; nob; Nyctalopin; Nyx
Gene Symbols NYX
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 282-481 of human NYX (NP_072089.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 236690, 60506
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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