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Invitrogen™ OAS1 Polyclonal Antibody
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Catalog No. PIPA541755
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100 μL
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Catalog No. Quantity
PIPA541755 100 μL
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Catalog No. PIPA541755 Supplier Invitrogen™ Supplier No. PA541755
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Description

Rabbit Polyclonal Antibody

Peptide sequence: MMDLRNTPAK SLDKFIEDYL LPDTCFRMQI NHAIDIICGF LKERCFRGSS Sequence homology: Cow: 86%; Dog: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 79%; Rabbit: 79%; Rat: 79%.

OAS1 is an interferon inducible protein that may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. It binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. This protein is associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OAS1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene OAS1
Gene Accession No. P00973
Gene Alias (2-5')oligo(A) synthase 1; (2-5')oligo(A) synthase 1A; (2-5')oligo(A) synthetase 1; (2-5')oligo(A) synthetase 1A; 2',5'-oligo A synthetase 1; 2',5'-oligoadenylate synthetase 1, 40/46kDa; 25 oligoadenylate synthetase; 2'-5' oligoadenylate synthetase; 2'-5' oligoadenylate synthetase 1; 2'-5' oligoadenylate synthetase 1A; 2'-5' oligoadenylate synthetase 1G; 2-5A synthase 1; 2-5A synthase 1A; 2-5A synthetase 1; 2-5A synthetase 1A; 2'-5'-oligoadenylate synthase 1; 2'-5'-oligoadenylate synthase 1; LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 1; 2'-5'-oligoadenylate synthase 1A; 2'-5'-oligoadenylate synthetase 1; 2-5-oligoadenylate synthetase 1; 2'-5'-oligoadenylate synthetase 1, 40/46kDa; 2'-5'-oligoisoadenylate synthetase 1; E16 (2'-5') oligo A synthetase; E18/E16; IFI 4; IFI4; IFI-4; L3; LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 1; OAS 1; Oas1; Oas1a; Oas1g; OIAS; Oias1; OIASI; p42 OAS; p46/p42 OAS
Gene Symbols OAS1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human OAS1 (aa 1-50).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4938
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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