OAS2 Monoclonal Antibody (OTI2G3), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA802825

Catalog No. 50-167-9435

Description

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2′-specific nucleotidyl transfer reactions to synthesize 2′,5′-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: OAS2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P29728
• Gene Symbols: OAS2
• Immunogen: Human recombit protein fragment corresponding to amino acids 60-335 of human OAS2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI2G3
• Conjugate: Unconjugated
• Gene: OAS2
• Gene Alias: 2′-5′-oligoadenylate synthetase 2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4939
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid