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Invitrogen™ OAS2 Polyclonal Antibody
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Catalog No. PIPA5110055
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100 μL
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PIPA5110055 100 μL
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Catalog No. PIPA5110055 Supplier Invitrogen™ Supplier No. PA5110055
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TQYQQLCIFW KVNYNFEDET VRKFLLSQLQ KTRPVILDPA EPTGDVGGGD RWCWHLLAKE AKEWLSSPCF KDGTGNPIPP WKVPTMQTPG SCGARIHPIV N.

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OAS2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.96 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene OAS2
Gene Accession No. P29728
Gene Alias (2-5')oligo(A) synthase 2; (2'-5')oligo(A) synthetase 2; 2',5'-oligoadenylate synthetase-like 11; 2,5-oligoadenylate synthetase-like 11; 2'-5' oligoadenylate synthetase 2; 2'-5' oligoadenylate synthetase-like 11; 2-5A synthase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; A synthetase 2; MGC78578; Oas2; Oasl11; p69 OAS / p71 OAS; p69OAS / p71OAS
Gene Symbols OAS2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 600-700 of human OAS2 (NP_0581972).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4939
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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